Selectivities in carbometalation of olefins . Experimental and theoretical studies
نویسندگان
چکیده
Despite the potential synthetic utility of the reaction, the elements that control the regioand stereochemistry of t he addition of a n organometallic reagent to an olefin have not received careful attention. Our recent studies on the selectivities in organometallic addition to cyclopropenone acetals have revealed some principles of regioand stereocontrol in organometallic additions to olefins. As guided by the computational analysis of the experimental selectivities, it was found that the controlling elements are quite different from those known for organometallic additions to carbonyl compounds.
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